Smallest light switches: Revolutionary research unfolds great potential!
Research by the TU Vienna and the University of Vienna on arylazopyrazole: innovative photoswitches for medicine and materials science.

Smallest light switches: Revolutionary research unfolds great potential!
What is happening on the front lines of modern research? An exciting project between the Vienna University of Technology and the University of Vienna has recently caused a stir: It's all about innovationPhotoswitch, which can be activated by light. Through more in-depth studies and experiments, the understanding of these molecular “light switches” is not only refined, but also significantly expanded.
Progress in this area is significant. The researchers discovered that certain molecules can switch between a stretched and a bent shape. These changes are more than just cosmetic - they directly affect the chemical properties of the molecules, opening up new applications in medicine, materials science and data storage. The potential of theArylazopyrazolesas promising photoswitches.
Fascination with arylazopyrazoles
What makes these arylazopyrazoles so special? They allow quantitative photoswitching and show high thermal stability, which is an impressive 1000 days. The absorption band maxima of the different isomers are clearly separated, which is why quantitative two-sided photoswitching is possible. Research results even demonstrate that two chiral S1/S0 conical interfaces have been identified that can well explain the dynamics of the excited states.
A highlight of the study is the discovery of the first example of near stereospecific unidirectional excited state relaxation for a specific arylazopyrazole derivative. The experimental data complements a theoretical model that was developed in cooperation between the two universities in Vienna and makes it possible to better understand and predict the switching behavior of these molecules.
In this way, a targeted adjustment of the lifespan of photoswitches can be achieved, which is a huge step, especially in photopharmacology. Here, light is used to specifically activate medications – what an advance in the targeted therapy of diseases!
Research goals and future perspectives
The studies were funded under the auspices of the Austrian Science Fund (FWF) and show how important interdisciplinary approaches are in research. Scientists from the TU Vienna and the University of Vienna combine their strengths to further advance the field of molecular switches. The results of this collaboration were recently published in the journalApplied Chemistrypublished and shed new light on the dynamics and potential of arylazopyrazole.
It seems as if these small chemical miracles could have a major impact on our future technologies, be it in electronics, materials research or even medicine. We can really look forward to future developments!