Viennese researchers discover new approaches to epilepsy attacks!

Viennese researchers discover new approaches to epilepsy attacks!

Wien, Österreich - A new approach in epilepsy research brings a breath of fresh air to the treatment of this widespread disease. Around 65 million people worldwide suffer from epilepsy, an illness caused by a disorder of excitation control in brain cells. In a recent study, the Medical University of Vienna discovered a molecular mechanism that could play a crucial role in the development of epileptic seizures. This mechanism, known as "Paroxysmale depolarization spurts" (PDS), is characterized by an increased electrical activity in the nerve cells and is viewed as harbinger of seizures. As reported by the [Medical University of Vienna] (https://www.meduniwien.at/web/ueber-uns/2025/news-im-juni-2025/epilepse--satz-fuer-urapy- therapy-erforscht/Medizin-Swissenschaft/) play.

The knowledge of the study shows that PDS occur particularly in the context of brain damage such as after a stroke or traumatic brain trauma and activate a protective mechanism in the hippocampus at short notice, which can, however, lead to seizure-like electrical discharges in the long term. So far, epilepsy attacks have been mostly symptomatic to suppress them. With the new information from the study published in the “Journal of Neuroscience”, however, it could be possible to develop preventive treatments for specific forms of epilepsy. According to the [Medical University of Vienna] (https://www.meduniwien.at/web/ueber-uns/2025/news-im-juni-2025/epilepse-fuer--ur therapy-erforscht/Medizin-Swissenschaft/), further studies are already being planned to advance.

A look behind the scenes of research

The Epilepsy working group, led by Prof. Dr. med. J. Rémi, deals with the improvement of diagnostics, therapy and forecast assessment of epilepsy. In research, the focus is also on semiological analysis and electroencephalography (EEG) in order to better classify and understand the different attack types. This is crucial for the diagnosis and localization of straps in focal epilepsy.

Another urge to innovate is shown in the use of the latest technologies, such as 3D procedures and AI methods for analyzing seizures. These approaches, according to the LMU Klinikum, help to understand and improve the effects of epilepsy on the quality of life of the patient. The combination of the latest technology and well -founded basic research is a promising basis for future developments in the therapy of this chronic neurological disease.

The further research will therefore be crucial in order not only to treat the symptoms of epilepsy, but also to combat the causes sustainably. The light at the end of the tunnel for many affected could become more tangible due to these new scientific knowledge.